Delta: A Toolset for the Structural Analysis of Biological Sequences on a 3D Triangular Lattice

نویسندگان

  • Minghui Jiang
  • Martin Mayne
  • Joel Gillespie
چکیده

The lattice approach to biological structural analysis was made popular by the HP model for protein folding, but had not been used previously for RNA secondary structure prediction. We introduce the Delta toolset for the structural analysis of biological sequences on a 3D triangular lattice. The Delta toolset includes a proof-of-concept RNA folding program that is both fast and accurate in predicting the secondary structures with pseudoknots of short RNA sequences.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Geometrical Parameters of Cylindrical Composite Lattice Structures on Buckling Behavior

Due to their light weights and high load carrying capacities, composite structures are widely used in various industrial applications especially in aerospace industry. Stiffening ribs are the main features of lattice type composite structures. Strength to weight ratio is known to be as one of the most critical design parameter in these structures. In this study, the effect of some parameters su...

متن کامل

Experimental and FEM Analysis of Ribs Defects on Composite Lattice Cylindrical Shells

In this study, the behavior of a composite lattice cylindrical shell is investigated in the buckling deforming. Also, the distribution of shell buckling response and the stress field is studied after making some defects on the ribs.Therefore using ANSYS software, a 3D finite element model of the shell has been created for the analysis. Material properties and geometrical data of the shell are o...

متن کامل

Comparing the Bidirectional Baum-Welch Algorithm and the Baum-Welch Algorithm on Regular Lattice

A profile hidden Markov model (PHMM) is widely used in assigning protein sequences to protein families. In this model, the hidden states only depend on the previous hidden state and observations are independent given hidden states. In other words, in the PHMM, only the information of the left side of a hidden state is considered. However, it makes sense that considering the information of the b...

متن کامل

Alternative approaches to obtain t-norms and t-conorms on bounded lattices

Triangular norms in the study of probabilistic metric spaces as a special kind of associative functions defined on the unit interval. These functions have found applications in many areas since then. In this study, we present new methods for constructing triangular norms and triangular conorms on an arbitrary bounded lattice under some constraints. Also, we give some illustrative examples for t...

متن کامل

Studies of protein designability using reduced models

One the most important problems in computational structural biology is protein designability, that is, why protein sequences are not random strings of amino acids but instead show regular patterns that encode protein structures. Many previous studies that have attempted to solve the problem have relied upon reduced models of proteins. In particular, the 2D square and the 3D cubic lattices toget...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2007